Top Definition
When a person decides to tell a love interest that they like them and get rejected, they become so depressed that instead of gaining weight they lose it.
(In honor of this kid who lost so much weight because he got rejected).
Pino: hey, have you noticed that Juan has lost a lot of weight?

Eddy: Oh, you didn't know? he suffered from Lance Syndrome. Some chick rejected him.
από Eddykid 24 Φεβρουάριος 2009
5 Words related to Lance Syndrome

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